De Neve, Jan-Emmanuel (2011) Functional polymorphism (5-HTTLPR) in the serotonin transporter gene is associated with subjective well-being: evidence from a US nationally representative sample. Journal of Human Genetics, 56. pp. 456-459.
Variation in the promotor region of the serotonin transporter gene (5-HTTLPR) is a promising candidate for better understanding individual heterogeneity in subjective well-being or happiness, as measured by life satisfaction. This functional polymorphism has previously been associated with mental health and selective processing of positive and negative emotional stimuli. A case–control association study on a representative sample of Americans (N¼2574) finds that individuals with the transcriptionally more efficient version of the serotonin transporter gene, report significantly higher levels of life satisfaction (P¼0.01). This new finding may help explain the important genetic component of the individual baseline levels of happiness.
|Keywords:||5-HTTLPR; happiness; life satisfaction; population genetics; serotonin transporter; subjective well-being|
|Subject(s):||Strategy; Entrepreneurship & Global business|
|Centre:||Faculty of Strategy, Entrepreneurship and International Business|
|Date Deposited:||11 Aug 2015 11:40|
|Last Modified:||23 Oct 2015 14:08|
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